Detalhe da pesquisa
1.
WNK kinases sense molecular crowding and rescue cell volume via phase separation.
Cell
; 185(24): 4488-4506.e20, 2022 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36318922
2.
DDX17 is involved in DNA damage repair and modifies FUS toxicity in an RGG-domain dependent manner.
Acta Neuropathol
; 142(3): 515-536, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34061233
3.
The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease.
Nat Rev Neurosci
; 17(6): 383-95, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27150398
4.
The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.
Nature
; 525(7567): 56-61, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26308891
5.
Optogenetic TDP-43 nucleation induces persistent insoluble species and progressive motor dysfunction in vivo.
Neurobiol Dis
; 146: 105078, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32927062
6.
C9orf72 nucleotide repeat structures initiate molecular cascades of disease.
Nature
; 507(7491): 195-200, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24598541
7.
Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity.
EMBO J
; 30(22): 4665-77, 2011 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21964071
8.
Axonally synthesized ß-actin and GAP-43 proteins support distinct modes of axonal growth.
J Neurosci
; 33(8): 3311-22, 2013 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23426659
9.
A HuD-ZBP1 ribonucleoprotein complex localizes GAP-43 mRNA into axons through its 3' untranslated region AU-rich regulatory element.
J Neurochem
; 126(6): 792-804, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23586486
10.
Disrupting pathologic phase transitions in neurodegeneration.
J Clin Invest
; 133(13)2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37395272
11.
Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit.
Neurol Ther
; 12(6): 1821-1843, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37847372
12.
Moderate intrinsic phenotypic alterations in C9orf72 ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features.
Front Cell Neurosci
; 17: 1179796, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37346371
13.
Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains.
bioRxiv
; 2023 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37732211
14.
Subcellular communication through RNA transport and localized protein synthesis.
Traffic
; 11(12): 1498-505, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21040295
15.
Axonal Localization of transgene mRNA in mature PNS and CNS neurons.
J Neurosci
; 31(41): 14481-7, 2011 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21994364
16.
Local translation in primary afferents and its contribution to pain.
Pain
; 163(12): 2302-2314, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35438669
17.
NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility.
Nat Commun
; 13(1): 3380, 2022 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35697676
18.
Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy.
Mol Neurodegener
; 17(1): 80, 2022 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36482422
19.
RNA modulates physiological and neuropathological protein phase transitions.
Neuron
; 109(17): 2663-2681, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34297914
20.
Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology.
Elife
; 102021 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34060470